Bacteroides uniformis beta-glucuronidase 2 covalently bound to cyclophellitol-6-carboxylate aziridine

Bacteroides uniformis beta-glucuronidase 2 covalently bound to cyclophellitol-6-carboxylate aziridine Descriptor: (1S,2R,3S,4S,5S,6R)-2-amino-3,4,5,6-tetrahydroxycyclohexane-1-carboxylic acid, Beta-galactosidase, CALCIUM ION, ... Authors: Pellock, S.J, Jariwala, P.B, Redinbo, M.R. Deposit date: 2019-02-13 Release date: 2019-12-18 Last modified: 2023-10-11 Method: X-RAY DIFFRACTION (2.43 Å) Cite: Discovering the Microbial Enzymes Driving Drug Toxicity with Activity-Based Protein Profiling. Acs Chem.Biol., 15, 2020

本数据集为单形拟杆菌(Bacteroides uniformis)β-葡萄糖醛酸苷酶2（beta-glucuronidase 2）与环菲糖醇-6-羧酸酯氮丙啶(cyclophellitol-6-carboxylate aziridine)的共价结合复合物。其描述符包括：(1S,2R,3S,4S,5S,6R)-2-氨基-3,4,5,6-四羟基环己烷-1-羧酸、β-半乳糖苷酶(Beta-galactosidase)、钙离子(CALCIUM ION)等。作者团队为Pellock, S.J.、Jariwala, P.B.、Redinbo, M.R.。沉积日期：2019-02-13；发布日期：2019-12-18；最后修改日期：2023-10-11。实验方法采用X射线衍射(X-RAY DIFFRACTION)，分辨率为2.43埃(Å)。引用文献：《基于活性的蛋白质谱分析发现驱动药物毒性的微生物酶》（Discovering the Microbial Enzymes Driving Drug Toxicity with Activity-Based Protein Profiling），发表于《ACS化学生物学(Acs Chem.Biol.)》2020年第15卷。