A) Mms4 peak locations at 5h time point in SK1 wild type strain.

Label indicates overlap of Mms4 peak with Spo11 peaks, Red1 peaks and centromeres. B) Mms4 peak locations at 5h time point in the spo11∆ mutant. Label indicates overlap of Mms4 peak with Spo11 peaks, Red1 peaks and centromeres. Nil indicates other regions. p value indicates statistical significance of the peaks, q value indicates the adjusted p value using Benjamini Hochberg correction. C) Mms4 peak locations at 5h time point in the red1∆ mutant. Label indicates overlap of Mms4 peak with Spo11 peaks, Red1 peaks and centromeres. Mms4 peaks with Nil label indicates other regions. p value indicates statistical significance of the peaks, q value indicates the adjusted p value using Benjamini Hochberg correction. D) Mms4 peak locations at 5h time point in the msh5∆ mutant. Label indicates overlap of Mms4 peak with Spo11 peaks, Red1 peaks and centromeres. Nil label indicates other regions. p value indicates statistical significance of the peaks, q value indicates the adjusted p value using Benjamini Hochberg correction. (XLSX)