Chromosomal aberrations identified in the six GSC lines through QFQ-banding and FISH analysis.

The aberrations identified and/or supported by FISH analysis are marked in red. -: loss of whole chromosome; +: gain of whole chromosome; ++: more than one sovrannumerary copy; –: loss of at least two copies of a chromosome;/: lack of alterations. All the numerical alterations are referred to the modal number of chromosomes for each cell line. Numbers in square brackets refer to percentages of each abnormality. From a minimum of 12 to a maximum of 34 metaphases were evaluated for each GSC line and the analysis was performed on at least 3 different passages.