Evaluation of natalizumab accumulations on lymphocyte subsets from individual patients at single time-points.

Abbreviations: ID, identification number; NK, natural killer cells; NKT, natural killer T cells; SD, standard deviation; T, time of measurement; Tx/T0, quotient of anti-natalizumab rfi levels of measurements performed during natalizumab therapy (T12,…,48) and background rfi levels from measurements performed at baseline (T0);Bold ID numbers highlight patients with reported disease activity; bold results highlight values above cut-off; bold results with plus signs highlight values above cut-off of patients with reported disease activity.1cut-off defined as sum of means plus one standard deviation.