Intergenerational effect of short-term spaceflight in mice
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https://www.ncbi.nlm.nih.gov/sra/DRP007383
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We investigated the effect of spaceflight on male germ cells and found that male mice that had experienced spaceflight exhibit alterations in binding of ATF7, a regulator of heterochromatin formation, on promoter regions in testis, as well as altered small RNA expression in spermatozoa. Offspring of space-traveling males exhibit elevated hepatic expression of genes related to DNA replication. Thus, spaceflight has intergenerational effect.
创建时间:
2021-06-13



