Baseline HIVDR mutations.
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https://figshare.com/articles/dataset/_Baseline_HIVDR_mutations_/769376
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∧None of the participants with drug resistance at baseline were switched to alternative first-line or second-line treatment during the 12 month follow-up. The treatment shown was initiated after the baseline HIVDR genotyping.
¥participant 1 showed baseline mutations, but was virologically suppressed at 12 months (see Table 4);
*M184V/I cause high-level in vitro resistance to 3TC.
**K103N and K103KN, A98AG and Y181CY cause high-level resistance to NVP and EFV. G190A causes high level resistance to NVP and intermediate resistance to EFV.
The drugs in bold and underlined have a reduced sensitivity against the mutated viruses.
Viral suppression is defined by VL≥1000copies/mL.
创建时间：
2013-08-12
