Enoyl-ACP Reductase from Plasmodium falciparum (PfENR) in complex with triclosan variant T2

Enoyl-ACP Reductase from Plasmodium falciparum (PfENR) in complex with triclosan variant T2 Descriptor: 5-(chloromethyl)-2-(2,4-dichlorophenoxy)phenol, Enoyl-ACP reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE Authors: Maity, K, Bhargav, S.P, Sankaran, B, Surolia, N, Surolia, A, Suguna, K. Deposit date: 2010-02-14 Release date: 2010-06-16 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (2.2 Å) Cite: X-ray crystallographic analysis of the complexes of enoyl acyl carrier protein reductase of Plasmodium falciparum with triclosan variants to elucidate the importance of different functional groups in enzyme inhibition Iubmb Life, 62, 2010

恶性疟原虫（Plasmodium falciparum）来源的烯酰-ACP还原酶（Enoyl-ACP Reductase，PfENR）与三氯生（triclosan）变体T2形成的复合物。描述信息：5-(氯甲基)-2-(2,4-二氯苯氧基)苯酚、烯酰-ACP还原酶、烟酰胺腺嘌呤二核苷酸（NICOTINAMIDE-ADENINE-DINUCLEOTIDE）。作者：Maity, K、Bhargav, S.P、Sankaran, B、Surolia, N、Surolia, A、Suguna, K。存入日期：2010-02-14；发布日期：2010-06-16；最后修改日期：2023-11-01。实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率2.2埃（Å））。引用文献：《恶性疟原虫烯酰酰基载体蛋白还原酶与三氯生变体复合物的X射线晶体学分析，以阐明不同官能团在酶抑制中的重要性》，IUBMB Life，第62卷，2010年。