Killing kinetics analysis of C-1311 derivative with octaarginine (Compound 1-R8) against Candida albicans

The datasets contain the results of killing kinetics analysis of imidazoacridinone derivative and fluconazole against C. albicans ATCC 10231. The suspensions of Candida albicans ATCC 10231 cells (500 µL) in RPMI 1640 at cell density of 104 cells /mL were added to 500 µL of RPMI 1640 medium with various concentrations of the compounds, corresponding to 8 MIC, 4 MIC, 2 MIC, MIC, 1/2 MIC, vigorously shaken, and then incubated at 37°C for 60, 180 and 300 min. After an appropriate time of incubation, 10µL was withdrawn and spread on YPD agar plates. The number of colony-forming units (CFUs) was determined after overnight incubation of the plates at 37°C.