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DOT1 like histone lysine methyltransferase (DOT1L) involvement in VSMC phenotypic switch in vitro

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NIAID Data Ecosystem2026-03-13 收录
下载链接:
https://www.ncbi.nlm.nih.gov/sra/SRP300898
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资源简介:
Dot1L plays a key role in the epigenetic control of VSMC gene expression, leading to atherosclerosis development. We aimed to determine whether Dot1L modulates primary VSMC phenotype in vitro and in vivo. Also, we assessed that Dot1L abrogation can induce expression changes of proliferation, cell-cycle regulation and inflammation-related genes.
创建时间:
2022-04-01
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