Insights into RNA modification and gene expression patterns of Acinetobacter baumannii during infection in Galleria mellonella

This research explores pathogenic bacterium Acinetobacter baumannii, a major health concern due to its increasing antibiotic resistance. To understand its infection mechanisms, this study investigated the virulence determinants through gene expression and RNA modifications analyses, utilising an insect infection model. The findings of this thesis provide insights that could aid in developing therapeutic strategies to combat this challenging pathogen.