Supplementary Material for: The Association of Proteinuria Target Achievement Timing and Stability with Adverse Kidney Outcomes Among Patients with IgA Nephropathy: A Cohort Study

Introduction: Current KDIGO guidelines for IgA nephropathy (IgAN) recommend proteinuria should be maintained at 50% decrease in eGFR from baseline. Results: In Part A, the primary outcome occurred in 166 (18.65%) patients. The 10-year kidney survival probability was 73% in TTT < 6 months group and 64% in TTT ≥ 6 months group (P=0.006). We identified a significant association between the rate of initial target achievement and clinical outcomes. In Part B, the primary outcome occurred in 385 (23.21%) patients. The 10-year kidney survival probability was 45% in T1 (TTR=0%); 60% in T2 (0%