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Epigenetic control of expression homeostasis during replication is stabilized by the replication checkpoint

NIAID Data Ecosystem2026-05-25 收录

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DNA复制检查点

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP150815 数据链接链接失效反馈

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In this study we reveal the roles of chromatin modifications and the DNA replication checkpoint in the mechanism that underlies buffering of gene expression against DNA dosage imbalance

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创建时间：

2018-06-19

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Histone modifiers instruct cellular differentiation, yet how they achieve temporal precision remains enigmatic. Here we demonstrate that the H3K27 demethylase Kdm6b acts as a master epigenetic conduct

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Epigenetic control of expression homeostasis during replication is stabilized by the replication checkpoint

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