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Effect of Shiga toxin (Stx) and glucosylceramide synthase inhibitor (Gb3i) treatments on SV40 transformed human kidney endothelial cells

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NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE205723
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To investigate the transcriptional changes caused by Stx1 and Stx2 in human kidney microvascular cells (HKMECs), and the effects of GCSi pre-treatment on Stx-mediated effects SV40-transformed HKMECs were grown to confluency in cell culture plates, with subsequent treatment with GCSi or vehicle, and then treated with either Stx1, Stx2 or vehicle.
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2024-01-25
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