Table S1 - Characterization of Neurophysiological and Behavioral Changes, MRI Brain Volumetry and 1H MRS in zQ175 Knock-In Mouse Model of Huntington's Disease

MRI volmetry power analysis in zQ175 and WT mice. Summary of the sample size needed to detect a 50% effect in the MRI volumetry for whole brain, striatum and cortex, and in the concentrations of selected MRS striatal metabolites with an alpha of 0.05 and a power of 0.8 for the heterozygote (HET) and homozygote (HOMO) mice at 12 months of age. N/A, not applicable. (DOC)