Additional file 1 of Unraveling the complex role of microglia in Alzheimer’s disease: amyloid β metabolism and plaque formation

Supplementary Material 1. Table S1. A summary of TREM2 genetic intervention studies organized by categories (TREM2 deficiency, upregulation, and loss-of-function (LOF) mutations). Different extraction methods were used for Aβ analysis: guanidine (Gdn), formic acid (FA), Triton X-100 (TX), phosphate-buffered saline (PBS), and Tris-buffered saline (TBS). The extracted fractions are abbreviated as"fxn". Changes in amyloid plaque burden and Aβ concentration compared to control conditions are indicated.