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Identification of microRNAs dysregulated in cellular senescence driven by endogenous genotoxic stress. Mus musculus

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NIAID Data Ecosystem2026-03-07 收录
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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA209989
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We compared microRNA (miRNA) expression in Ercc1-/- primary mouse embryonic fibroblasts (MEFs) and wild-type (WT) MEFs in 20% O2 and 3% O2 growth conditions to identify miRNAs that drive cellular senescence. Overall design: MicroRNA expression in WT and Erccc1-/- MEFs was measured at passage 3 and passage 7 after growth in 20% and 3% O2. Two independent experiments were performed for each growth condition.
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2013-06-28
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