Top age at onset (AAO) meta-analysis results for the <i>FOXO1</i> region.

1Position for genome build 36.3 (hg18). 2Required p-value level for significance p-values = 8.68E-5; bold indicates significant p-value. 3Direction of effects are listed in the following order: PROGENI/GenePD, NIA Phase I, NIA Phase II, LEAPS, HIHG, NGRC; a question mark (?) indicates that the marker failed imputation (Rsq<0.30). 4Values for imputed (I) or genotyped (G) status. 5The meta-analysis included the PROGENI/GenePD, NIA Phase I, NIA Phase II, HIHG, and NGRC studies. 6The SNPExpress database [29] was used to look up eSNP relationships between the expression of FOXO1 transcripts or exons and the SNPs of interest. The best FOXO1 eSNP result is displayed if a p-value<0.05 was observed. The presented eSNP results were obtained in brain tissue. N/A values are used when the SNPs were not available in the database.