Epigenetic and metabolic reprogramming by HDAC inhibition targets NRF2-active tumors [CRISPR Screen]
收藏NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP412759
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资源简介：
To identify NRF2-specific dependencies in chromatin regulation, we performed a focused genetic screen mouse LUAD cell lines with or without knock-out of KEAP1. Overall design: A chromatin-focused CRISPR/Cas9 dropout screen was performed in 2 KP and 2 KPK cell lines and sgRNA enrichment was assessed by deep-sequencing at 0(t0) and 14(t1) population doublings.
创建时间：
2024-02-16
