AgingReG

AgingReG is a manually curated database focusing on regulatory relationships during aging with experimental evidence in humans. It includes 2157 entries comprising aging genes, external factors, and aging-related pathways. The database categorizes regulatory relationships into upregulation, downregulation, activation, and inhibition, covering 195 disease types and over 800 cell and tissue types.AgingReG（AgingReG）是一个经人工整理的数据库，聚焦于人类衰老过程中的调控关系，并收录了相关实验证据。该数据库共包含2157条条目，涵盖衰老基因、外部因素以及衰老相关通路。该数据库将调控关系划分为上调、下调、激活与抑制四类，覆盖195种疾病类型以及800余种细胞与组织类型。

搜集汇总

背景与挑战

背景概述

AgingReG是一个专注于人类衰老过程中调控关系的手动整理数据库，包含2157个条目，涵盖衰老基因、外部因素和衰老相关通路。它将调控关系分为上调、下调、激活和抑制四种类型，覆盖195种疾病类型和超过800种细胞与组织类型，数据来源于1784篇已发表文献。该数据库提供查询、浏览和可视化功能，以支持衰老调控机制的深入研究。