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The oncogenic role of HBV-targeted gene MLL4 in pancreatic cancer

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NIAID Data Ecosystem2026-05-02 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP444602
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By using a high-throughput viral integration detection approach (HIVID), a total of 425 HBV integration sites are identified, among which mixed lineage leukemia gene 4 (MLL4) is found to be repeatedly targeted by HBV in both HCC and PDAC. We found a critical role for MLL4 in promoting PDAC growth and metastasis.
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2025-07-27
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