Crystal structure of AfOgg1:8OG-DNA duplex in a product-bound state

Crystal structure of AfOgg1:8OG-DNA duplex in a product-bound state Descriptor: 8-oxoguanine DNA glycosylase/AP lyase, DNA (5'-D(*TP*GP*CP*AP*GP*GP*TP*CP*GP*AP*CP*TP*CP*TP*A)-3'), DNA (5'-D(P*AP*CP*CP*TP*GP*CP*A)-3'), ... Authors: Arvai, A.S, Syed, A, Huffman, J.L, Mol, C.D, Hitomi, K, Tainer, J.A. Deposit date: 2025-04-01 Release date: 2026-04-15 Last modified: 2026-08-05 Method: X-RAY DIFFRACTION (2 Å) Cite: A unified catalytic mechanism in bifunctional DNA glycosylases with an evolutionarily conserved aspartate-lysine dyad. Nat Commun, 2026