Design, Synthesis, and Characterization of SO2‑Containing Azabicyclo[3.n.1]alkanes: Promising Building Blocks for Drug Discovery
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https://figshare.com/articles/dataset/Design_Synthesis_and_Characterization_of_SO_sub_2_sub_Containing_Azabicyclo_3_i_n_i_1_alkanes_Promising_Building_Blocks_for_Drug_Discovery/2175859
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A set of novel SO2-containing azabicyclo[3.n.1]alkanes has been synthesized by the double-Mannich annulation of of the corresponding monocyclic S-ketones. These compounds have been rationally designed as 3D-shaped, conformationally restricted SO2-containing building blocks for drug discovery.
创建时间:
2016-02-13



