Dataset for "A serum protein network predicts the need for systemic immunomodulatory therapy in autoimmune uveitis"

This dataset contains *SOMAscan* targeted proteomics (1305 protein analytes) of serum of 54 patients with non-infectious uveitis (<i>HLA-B27+ anterior uveitis</i>, <i>idiopathic intermediate uveitis</i>, <i>HLA-A29+ Birdshot chorioretinopathy</i>, and 26 sex/age matched healthy controls without ocular inflammatory disease. The raw data files (<i>adat</i> files with relative fluorescent units for 1305 DNA aptamers for 80 samples), metadata, supplemental table 1-3, and R scripts (markdowns) as presented in: <br></br><i>Kuiper et al. 2021 "A serum protein network predicts the early need for systemic immunomodulatory therapy in non-infectious uveitis"</i> <dl>see preprint on <a href="https://medrxiv.org/cgi/content/short/2021.09.22.21263286v1"><i>MedRxiv</i></a>
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This dataset contains: <br></br>
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<dt>Supplemental Table 1-3</dt>
<ul><li><dd><a href="https://dataverse.nl/api/access/datafile/269069">Supplemental table 1-3.xml </a> <sup> xml file </sup></dd></li>
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<dt>Raw SOMAscan data</dt>
<ul><li><dd><a href="https://dataverse.nl/api/access/datafile/140933">MED-17-274.hybNorm.plateScale.medNorm.calibrate.20180425.adat</a> <sup> adat file </sup></dd></li>
<li><dd><a href="https://dataverse.nl/api/access/datafile/140940">SOMAscan Quality Statement</a><sup> PDF file </sup></dd></li></ul>

<dt>R scripts with <i>step-by-step</i> analyses </dt>
<ul><li><dd> "Figure_1.rmd" (see also <a href="https://dataverse.nl/api/access/datafile/141035">"Figure_1.html"</a>)</dd></li>
<li><dd>"Figure_2.rmd" (see also <a href="https://dataverse.nl/api/access/datafile/141031">"Figure_2.html"</a>)</dd></li>
<li><dd>"Figure_3.rmd" (see also <a href="https://dataverse.nl/api/access/datafile/141032">"Figure_3.html"</a>)</dd></li></ul>
<dt>Metadata used in the R scripts (above)</dt>
<ul><li><dd>This includes <a href="https://dataverse.nl/file.xhtml?fileId=140934&version=DRAFT">data</i> </a> generated by <a href="https://www.nature.com/articles/ni.3693"><i> Rieckmann et al., Nat Immunol. 2018</i> </a></li>
<li><dd>This includes <a href="https://dataverse.nl/file.xhtml?fileId=140935&version=DRAFT">data</i> </a> generated by <a href="https://www.science.org/doi/full/10.1126/science.aaq1327"><i> Emilsson et al., Science 2018</i> </a></li>
<li><dd>This includes <a href="https://dataverse.nl/file.xhtml?fileId=140928&version=DRAFT">data</i> </a> generated by <a href="https://academic.oup.com/nar/article/46/D1/D661/4612963"><i> Selenter et al., Nucleic Acids Res. 2018 </i> </a></li>
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