Crystal structure of a human cytochrome P450 2B6 (Y226H/K262R) in complex with the inhibitor 4-(4-Nitrobenzyl)pyridine.
收藏Protein Data Bank Japan2023-09-13 更新2026-03-21 收录
下载链接：
https://pdbj.org/mine/summary/3qu8
下载链接
链接失效反馈官方服务：
资源简介：
Crystal structure of a human cytochrome P450 2B6 (Y226H/K262R) in complex with the inhibitor 4-(4-Nitrobenzyl)pyridine. Descriptor: 4-(4-nitrobenzyl)pyridine, 5-CYCLOHEXYL-1-PENTYL-BETA-D-MALTOSIDE, Cytochrome P450 2B6, ... Authors: Shah, M.B, Pascual, J, Stout, C.D, Halpert, J.R. Deposit date: 2011-02-23 Release date: 2011-09-21 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structures of Cytochrome P450 2B6 Bound to 4-Benzylpyridine and 4-(4-Nitrobenzyl)pyridine: Insight into Inhibitor Binding and Rearrangement of Active Site Side Chains. Mol.Pharmacol., 80, 2011
携带Y226H/K262R突变的人细胞色素P450 2B6（cytochrome P450 2B6）与抑制剂4-(4-硝基苄基)吡啶结合的晶体结构。数据集描述符：4-(4-硝基苄基)吡啶、5-环己基-1-戊基-β-D-麦芽糖苷、细胞色素P450 2B6等。作者：Shah, M.B、Pascual, J、Stout, C.D、Halpert, J.R。提交日期：2011-02-23。发布日期：2011-09-21。最后修改日期：2023-09-13。实验方法：X射线衍射（分辨率2.8 Å）。引用文献：《结合4-苄基吡啶与4-(4-硝基苄基)吡啶的细胞色素P450 2B6结构：揭示抑制剂结合与活性位点侧链重排机制》，Mol.Pharmacol., 80, 2011
创建时间：
2011-02-23
