CHARACTERISTICS OF IMMUNOLOGICAL SHIFTS IN COMMUNITY-ACQUIRED PNEUMONIA IN FREQUENTLY ILL CHILDREN

The clinical and immunological status was assessed in 30 children aged 1 to 3 years who developed community-acquired pneumonia. It was revealed that in frequently ill children with community-acquired pneumonia, immunological shifts are characterized by a decrease in CD3, CD4, CD8, LNK16, PHA, IgA, an increase in CD19, IgM, IgG, CIC, which partially persist during the remission period. The decrease in IgA and increase in CIC concentration in blood serum indicate the immunocompromised state of the body and can serve as criteria for early immunodiagnosis of community-acquired pneumonia in frequently ill children.