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In vitro proteomic expression changes in Ewing sarcoma cell lines after mTOR blockade

ChEBI2016-06-01 更新2026-07-12 收录

尤文肉瘤蛋白质组学

mTOR抑制剂机制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-78122 数据链接链接失效反馈

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资源简介：

In vitro proteomic expression changes in Ewing sarcoma cell lines after mTOR blockade

应用场景：

创建时间：

2016-06-01

癌症放射增敏

mTOR抑制剂机制

Peptide receptor radioligand therapy (PRRT) has evolved as an important second-line treatment option in the management of inoperable and metastatic neuroendocrine neoplasms (NEN). Though high radiatio

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structure of mTORDeltaN-mLST8-PI-103 complex

蛋白质结构解析

mTOR抑制剂机制

structure of mTORDeltaN-mLST8-PI-103 complex Descriptor: 3-(4-MORPHOLIN-4-YLPYRIDO[3',2':4,5]FURO[3,2-D]PYRIMIDIN-2-YL)PHENOL, mLST8, mTOR Authors: Pavletich, N.P, Yang, H. Deposit date: 2013-03-22 Re

Protein Data Bank Japan2024-02-28 更新50

Comparative study of a mTOR inhibitor, a pan-PI3K inhibitor and a dual PI3K/mTOR inhibitor in MCL. Homo sapiens

淋巴瘤治疗

mTOR抑制剂机制

Phosphatidylinositol-3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathway activation contributes to mantle cell lymphoma (MCL) pathogenesis and drug resistance. However, the use of mTOR in

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FKBP12 mutant V55G bound to Rapa*-3Z

蛋白质-药物相互作用

mTOR抑制剂机制

FKBP12 mutant V55G bound to Rapa*-3Z Descriptor: (3S,5Z,6R,7E,9R,10R,12R,14S,15E,17E,19E,21S,23S,26R,27R,30R,34aS)-5-(ethoxyimino)-9,27-dihydroxy-3-{(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]pr

Protein Data Bank Japan2023-10-18 更新60

Table S6 from PQR309 Is a Novel Dual PI3K/mTOR Inhibitor with Preclinical Antitumor Activity in Lymphomas as a Single Agent and in Combination Therapy

淋巴瘤靶向治疗

mTOR抑制剂机制

Phosphoprotein changes induced by PQR309 in B cell lymphoma cell lines revealed using Reverse Phase Protein Array (RPPA) analysis.

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