OPTIMIZED CRISPR-CAS DOUBLE NICKASE SYSTEMS， METHODS AND COMPOSITIONS FOR SEQUENCE MANIPULATION
收藏国家林业和草原科学数据中心2023-02-12 更新2024-03-07 收录
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资源简介：
PROBLEM TO BE SOLVED: To provide the delivery， engineering and optimization of systems， methods， and compositions for manipulation of sequences and/or activities of target sequences. SOLUTION: Provided is a composition for use in modifying an eukaryotic cell by minimizing off-target modifications by manipulation of first and second target sequences on opposite strands of a DNA duplex in a genomic locus of interest in the eukaryotic cell， the composition modifying the eukaryotic cell by minimizing off-target modification. SELECTED DRAWING: None
提供机构：
国家林业和草原科学数据中心
创建时间：
2023-02-12
