Resuscitative endovascular balloon occlusion of the aorta (REBOA) minimal dataset

Introduction Resuscitative endovascular balloon occlusion of the aorta (REBOA) may be used in severely injured patients with uncontrollable bleeding. However, zone dependent effects of REBOA are rarely described. We compared the short-term zone- and organ-specific microcirculatory changes in abdominal organs and the extremity during occlusion of the aorta in a standardized porcine model. Methods Male pigs were placed under general anesthesia, for median laparotomy to expose intra-abdominal organs. REBOA placement occurred in Zone 1 (from origin left subclavian artery to celiac trunk), Zone 2 (between the coeliac trunk and most caudal renal artery) and Zone 3 (distal most caudal renal artery to aortic bifurcation). Local microcirculation of the intra-abdominal organs were measured at the stomach, colon, small intestine, liver, and kidneys. Further, the right medial vastus muscle was included for assessment. Microcirculation was measured using oxygen-to-see device (arbitrary unit...引言 复苏性主动脉球囊阻断术（Resuscitative endovascular balloon occlusion of the aorta, REBOA）可应用于存在不可控出血的重症创伤患者。然而，REBOA的区域依赖性效应鲜有文献报道。本研究借助标准化猪模型，对比了主动脉阻断期间腹部脏器与肢体的短期区域特异性及器官特异性微循环变化。 方法 雄性实验猪接受全身麻醉，行正中剖腹术以暴露腹腔内脏器。将REBOA分别放置于1区（左锁骨下动脉起始处至腹腔干）、2区（腹腔干与最尾侧肾动脉之间）及3区（最尾侧肾动脉至主动脉分叉处）。于胃、结肠、小肠、肝脏及肾脏处测量腹腔内脏器的局部微循环；此外纳入右股内侧肌进行微循环评估。微循环检测采用Oxygen-to-See设备完成（单位：任意单位……）