Markers showing a significant CD association in the case-control and the family-based analyses in panel B.

P-values obtained in an allele- (pCCA) or genotype-based (pCCG) case-control comparison in panel A are shown. Also included are pCCA, pCCG, and the TDT results (pTDT) for replication panel B. Nucleotide positions refer to NCBI build 35. Known susceptibility loci for CD are highlighted by bold type. A complete list of all 200 genotyped SNPs is given in Table S2. MAFco and MAFca denote the minor allele frequency in controls and cases, respectively. Rank: rank of SNP according to the p-value obtained in screening panel A. Odds Ratios (OR) and corresponding 95% confidence intervals (95% CI) are given for carriership of the rare allele of each SNP.