Neisseria gonorrhoeae with knock-out of NgoAXP (ngo0545::km) and NgoAV (ngo406::cm) Restriction-modification system versus wild type. Neisseria gonorrhoeae

Transcriptional profiling of N. gonorrhoeae comparing wild type cells to cells with inactivated by kanamycin cassette (km) gene involved in restriction modification NgoAXP or with chloramphenicol cassette (cm) gene involved in restriction-modification NgoAV. The Goal was to study the role of M.NgoAXP and NgoAV methyltransferases in overall expression profile. Overall design: Two-condition experiment, wild type cells vs. mutant cells . Biological replicates: 4 control replicates, 4 mutant replicates.