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[3 + 2] Cycloaddition of Oxazol-5-(4H)‑ones with Nitrones for Diastereoselective Synthesis of Isoxazolidin-5-ones

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Figshare2016-12-19 更新2026-04-29 收录
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https://figshare.com/articles/dataset/_3_2_Cycloaddition_of_Oxazol-5-_4_i_H_i_ones_with_Nitrones_for_Diastereoselective_Synthesis_of_Isoxazolidin-5-ones/4483070
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In the presence of TMSCl, the [3 + 2] cycloaddition of oxazol-5-(4H)-ones with nitrones proceeded smoothly and furnished the desired isoxazolidin-5-ones with high diastereoselectivities in reasonable chemical yields. The chemical structure of the title compounds was firmly confirmed by X-ray single-crystal structure analysis.
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2016-12-19
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