five

distinct mesenchymal cell states mediate prostate cancer progression

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NIAID Data Ecosystem2026-05-01 收录
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https://zenodo.org/record/7452769
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These are the count matrices (in .h5ad format) used to produce the results and figures in the paper entitled "distinct mesenchymal cell states mediate prostate cancer progression".  adata_mouse.h5ad: the normalized count matrix and cell annotations for the mesenchymal prostate data from all mouse models. adata_mouse_myo.h5ad: the normalized count matrix for the myofibroblasts and pericytes (both are c0). scenic_mesenchyme_auc.csv: the auc matrix of the regulons activity in the different cells and clusters in the mouse mesenchymal data. scenic_mesenchyme_binary.csv: the binary matrix of regulons activity in the mouse mesenchymal data. adata_human.h5ad: the normalized count matrix and cell annotations for the mesenchymal human primary prostate cancer data. adata_human_boneMet_stroma.h5ad: the normalized count matrix and cell annotation for the bone metastasis data derived from Kfoury et al. visium_PRN.h5ad: the normalized count matrix and cell annotation for the Visium spatial transcriptomics data of the PRN mouse model. visium_WT.h5ad: the normalized count matrix and cell annotation for the Visium spatial transcriptomics data of the WT (PRN-WT) mouse model. natHistory_expression: the normalized expression matrix for the natural history cohort. natHistory_label: the metastasis indicators for the natural history cohort.
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2023-11-03
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