Cryo-EM structure of human norepinephrine transporter NET in the presence of norepinephrine in an inward-open state at resolution of 2.9 angstrom.

Cryo-EM structure of human norepinephrine transporter NET in the presence of norepinephrine in an inward-open state at resolution of 2.9 angstrom. Descriptor: L-NOREPINEPHRINE, Sodium-dependent noradrenaline transporter Authors: Tan, J, Xiao, Y, Kong, F, Lei, J, Yuan, Y, Yan, C. Deposit date: 2022-11-10 Release date: 2024-05-15 Last modified: 2025-07-23 Method: ELECTRON MICROSCOPY (2.86 Å) Cite: Molecular basis of human noradrenaline transporter reuptake and inhibition. Nature, 632, 2024分辨率为2.9埃的内向开放构象下结合去甲肾上腺素的人源去甲肾上腺素转运体（NET）的冷冻电镜（Cryo-EM）结构。描述符：L-去甲肾上腺素、钠依赖性去甲肾上腺素转运体。作者：Tan J、Xiao Y、Kong F、Lei J、Yuan Y、Yan C。提交日期：2022-11-10。发布日期：2024-05-15。末次修改日期：2025-07-23。实验方法：电子显微镜（分辨率2.86埃）。引用文献：《人源去甲肾上腺素转运体再摄取与抑制的分子基础》，《自然》（Nature），第632卷，2024年