Draft Updated Test Guideline 497 for inclusion of SARA-ICE Defined Approach for derivation of Quantitative Point of Departure

Organisation for Economic Co-operation and Development2026-04-11 收录

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https://www.oecd.org/en/events/public-consultations/2024/10/draft-updated-test-guideline-497-for-inclusion-of-sara-ice-defined-approach-for-derivation-of-quantitative-point-of-departure.html

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The objective of this project is to include SARA-ICE DA in Test Guideline 497 (TG 497) to establish a point of departure for quantitative risk assessment. This would be a novel addition to the current version of the TG 497, which currently contains rule-based hazard classification and GHS potency classification models. The SARA model is a...