DEG from Bulk RNA seq and Western Blot images of cardiomyocyte-specific cytoplasmic b/g1 actin knockout mouse
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To demostrate the imporrtance of cytoplasmic actin networks in adult cardiomyocytes, we generated cardiomyocyte-specific Actb ad Actg1 double knockout mouse with Cre-loxP system. Western blots confirmed down-regulations of b-aactin and g-actin in the isolated cardiomyocytes. We also carried out bulk RNA-seq using total RNA extrracted from the hearts and assessed transcriptional landscape.
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2026-06-22



