The <i>IL28B</i> SNP, rs12979860, is associated with HCV treatment response in a cohort of HCV/HIV-1 co-infected patients.

Patients that completed therapy were genotyped for the IL28B SNP (rs12979860) using a Taqman allele discrimination assay. Genotype frequencies were compared between patients who achieved SVR following treatment (n = 101) and those who did not achieve SVR (n = 48). Differences in frequency distribution between groups were tested for significance by a trend test. 1Genotype for a subset of these patients, n = 72, has previously been described (Reference 16)