BK Polyomavirus VP1 pentamer fusion with long C-terminal extended arm
收藏Protein Data Bank Japan2024-01-31 更新2026-03-21 收录
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BK Polyomavirus VP1 pentamer fusion with long C-terminal extended arm Descriptor: CALCIUM ION, DIMETHYL SULFOXIDE, Major capsid protein VP1,Major capsid protein VP1 Authors: Osipov, E.M, Beelen, S, Strelkov, S.V. Deposit date: 2020-12-07 Release date: 2022-06-22 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.484 Å) Cite: Discovery of novel druggable pockets on polyomavirus VP1 through crystallographic fragment-based screening to develop capsid assembly inhibitors. Rsc Chem Biol, 3, 2022
BK多瘤病毒(BK Polyomavirus)VP1五聚体与长C端延伸臂融合体
组分描述:钙离子(CALCIUM ION)、二甲基亚砜(DIMETHYL SULFOXIDE)、主要衣壳蛋白VP1(Major capsid protein VP1)、主要衣壳蛋白VP1
作者:Osipov E.M.、Beelen S.、Strelkov S.V.
存档日期:2020-12-07
发布日期:2022-06-22
最后修改日期:2024-01-31
实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率2.484埃
引用文献:通过基于晶体片段筛选的方法在多瘤病毒VP1上发现新型可药物结合口袋,以开发衣壳组装抑制剂。《RSC化学与生物学》(Rsc Chem Biol),第3卷,2022年
创建时间:
2020-12-07



