We compared gut microbiota of IFI16 KO and WT mice by 16s sequencing

To investigate whether gut microbiota is associated with IFI16, 16 fecal samples from widetype mice (WT) (n=8) and IFI16 knockout mice (IFI16 KO) (n=8) two groups, Illumina MiSeq pyrosequencing analysis and bioinformatic statistical approach demonstrated that the diversity of gut microbiota and key pholytypes are significantly different in WT mice and IFI16 KO mice