Nitrogen-Containing Lanthanide Metal–Organic Framework Nanostructure for Fluorescent Detection of Lamotrigine

The
rational design and exploitation of fluorescent nanomaterials
with excellent properties is of great significance for the detection
of lamotrigine (LTG). Herein, a novel lanthanide metal–organic
framework was prepared via the self-assembly of a Tb3+ ion
and an H2DimTA ligand. The as-prepared material exhibits
a lamellar nanostructure with plenty of pyrazole nitrogen sites (specific
recognition sites for LTG), which can directly act as fluorescence
detectors toward LTG detection. Their outstanding performance with
a low limit of detection (1.89 μM), superior anti-interference
capability, rapid response, and excellent durability shows their great
potential in the field of fluorescence detection.