Lysine methylation of EHMT1/GLP as a molecular switch to reprogram transcription networks in prostate cancer [RNA-seq UNC0642]
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE225068
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Our studies provide novel molecular insights into the activity and function of EHMT1 during PCa progression and suggest a novel therapeutic strategy to treat CRPC with EHMT1 inhibitors. LNCaP-tet-EHMT1 cells were treated with/out 0.5ug/mL docxycycline and 2uM UNC0642 for two days. LNCaP cells were treated with siNTC, SiEHMT2 at 20nM for two days. All RNA-seq samples contain replications.
创建时间:
2023-09-14



