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Systematic identification of cancer cell vulnerabilities to natural killer cell-mediated immune surveillance

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NIAID Data Ecosystem2026-04-25 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP214323
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资源简介:
RNA-seq analysis of the transcriptome of K562 cells in which PTPN2 or DCAF15 had been disrupted by CRISPR/cas9 gene editing. Overall design: K562 cells expressing cas9 were infected with lentiviruses expressing sgRNAs against a control gene, PTPN2 or DCAF15. Two weeks after sgRNA infection cells were plated at 0.33M cells/ml and either left alone or treated with 10ng/ml IFNg for 24hrs
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2019-09-29
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