UGT1A1 Sanger sequencing data from Tibetan and Han Chinese newborns
收藏DataCite Commons2025-07-02 更新2025-09-08 收录
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https://figshare.com/articles/dataset/__UGT1A1_Sanger_/29446256/3
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This dataset is related to the study <i>“Analysis of UGT1A1 Polymorphisms and Clinical Risk Factors for Neonatal Jaundice in Tibetan Newborns: A Comparative Study with Han Newborns in China.”</i> It includes raw sequencing chromatograms (.ab1 files), aligned sequences (.fasta files), and summary tables of genotypes and clinical data.Umbilical cord blood samples were collected from Tibetan and Han Chinese newborns at the Maternal and Child Health Hospital of Shannan City, Tibet, between January 2024 and April 2025. Genomic DNA was extracted and genotyped using Sanger sequencing for three UGT1A1 variants: c.211G>A, the (TA)n promoter repeat, and c.-3279T>G.Clinical parameters such as birth weight, gestational age, mode of delivery, and transcutaneous bilirubin levels were recorded. The study was approved by the Ethics Committee of Yangtze University, and written informed consent was obtained from the parents of all participants.This dataset supports reproducibility and further research into the genetic and environmental risk factors of neonatal jaundice in high-altitude populations.
提供机构:
figshare
创建时间:
2025-07-02



