Crystal Structure of Human Liver Carboxylesterase complexed to Etyl Acetate; A Fatty Acid Ethyl Ester Analogue
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Crystal Structure of Human Liver Carboxylesterase complexed to Etyl Acetate; A Fatty Acid Ethyl Ester Analogue Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, CES1 protein, ETHYL ACETATE, ... Authors: Fleming, C.D, Bencahrit, S, Edwards, C.C, Hyatt, J.L, Morton, C.L, Howard-Williams, E.L, Potter, P.M, Redinbo, M.R. Deposit date: 2004-12-17 Release date: 2005-08-02 Last modified: 2024-10-09 Method: X-RAY DIFFRACTION (3 Å) Cite: Structural insights into drug processing by human carboxylesterase 1: tamoxifen, mevastatin, and inhibition by benzil. J.Mol.Biol., 352, 2005
人肝脏羧酸酯酶与乙酸乙酯（Ethyl Acetate）结合形成的复合物的晶体结构；该复合物对应一种脂肪酸乙酯类似物。相关描述物包括：2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖（2-acetamido-2-deoxy-beta-D-glucopyranose）、CES1蛋白、乙酸乙酯（Ethyl Acetate）等。作者：Fleming, C.D、Bencahrit, S、Edwards, C.C、Hyatt, J.L、Morton, C.L、Howard-Williams, E.L、Potter, P.M、Redinbo, M.R。入库日期：2004-12-17，发布日期：2005-08-02，最后修改日期：2024-10-09。实验方法：X射线衍射（3 Å）。引用文献：《人羧酸酯酶1介导药物加工的结构解析：他莫昔芬、美伐他汀及苯偶酰的抑制机制》，《分子生物学杂志》（J.Mol.Biol.），第352卷，2005年
创建时间：
2004-12-17
