DIS3 ablation in spermatocytes causes defective spermatogenesis in mice
收藏Alliance of Genome Resources2026-08-01 收录
官方服务：
资源简介：
Conditional inactivation of DIS3 in spermatocytes impairs meiotic progression and causes defective spermatogenesis in mice. scRNA-seq analysis indicates that DIS3 mutation significantly impairs spermatocytes meiotic progression and dysregulates transcriptome in spermatocytes. We show that DIS3 ribonuclease plays critical roles in male meiotic progression and spermatogenesis in mice.
