Ancestral codon configurations underlying ECC_uppppp and ECC_puuuuu trees

aExtant codon configurations (ECC) from Figure 4.
bequilibrium (1x), decreasing (1/3Ne), and increasing (2Ne) codon bias simulations.
cInitial values of major codon usage (at the mstyeo node).
dNumbers of observations of each ECC and the numbers (proportions) of ancestral codon arrangements (ACC) underlying the ECC's (B, C, D and F, G, H correspond to ACC's shown in Figure 4). The numbers are pooled across 300 replicates and only trees with two different codon states among all nodes are included.