Raw data for: GRADE and CINeMA showed moderate to substantial concordance in the evaluation of certainty of the evidence

Since 2014, two approaches have been developed to assess the certainty of the evidence of network meta-analysis results: the approach developed by the Grading of Recommendations Assessment, Development and Evaluation (GRADE) and the Confidence in Network Meta-Analysis (CINeMA) approach, inspired by the methodology developed by the GRADE Working Group.
GRADE and CINeMA were applied to four networks of different sizes and structures related to different outcomes in different clinical conditions and settings by 13 evaluators.
All domains in CINeMA have three levels of ratings (i.e. no concern, some concerns or major concerns). GRADE has also three levels of ratings (i.e. not serious, serious and very serious) except for two domains: publication bias has two (i.e. undetectable versus strongly detectable), and imprecision has four ratings (i.e. not serious, serious, very serious and very very serious).

自2014年起，针对网络荟萃分析结果的证据确定性评估，已发展出两种方法：由建议评估、开发与评价分级系统（GRADE）提出的方法，以及受GRADE工作组方法论启发的网络荟萃分析置信度（CINeMA）方法。GRADE与CINeMA已由13位评估者应用于四个规模和结构各异、与不同临床条件和环境相关联的结局的网络。CINeMA的所有领域均包含三个评级等级（即无顾虑、存在顾虑或重大顾虑）。GRADE亦设有三个评级等级（即非严重、严重及极为严重），除两个领域外：发表偏倚包含两个等级（即不可检测与强烈可检测），而精确度则包含四个评级（即非严重、严重、极为严重及极为极为严重）。