(A) Survival rates of mice prenatally treated with saline (white circle), fluvoxamine (gray triangle) or fluoxetine (black square) from 1 to 20 days after birth
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81% of the fluoxetine-treated offspring died within 20 days after birth. (B) HE-staining of a horizontal section of the hearts showed dilated cardiomyopathy in fluoxetine-treated offspring. (C) Wt/r ratios of the left ventricle presented as mean�S.E.M for groups treated with saline (white bars), fluvoxamine (gray bars) and fluoxetine (black bars) at P20 (N?=?6 for saline and fluvoxamine, N?=?4 for fluoxetine) and adulthood (N?=?5 for saline and fluvoxamine, N?=?3 for fluoxetine). Wt/r?=?wall thickness/radius, * p<b>Copyright information:</b>Taken from "Modulation of Serotonin Transporter Function during Fetal Development Causes Dilated Heart Cardiomyopathy and Lifelong Behavioral Abnormalities"PLoS ONE 2008;3(7):-.Published online 23 Jul 2008PMCID:PMC2518512.Noorlander et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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figshare
创建时间:
2016-01-11



