Additional file 1 of Human umbilical cord mesenchymal stem cell-derived exosomes promote microcirculation in aged diabetic mice by TGF-β1 signaling pathway

Additional file 1: Fig. 1 Changes in blood glucose and weight before and after treatment in EXO PBS groups. Fig. 2 Identification of exosomes of hUCMSCs. Fig. 3 Exosome therapy reduced the microvascular permeability of lower limb muscles in diabetic mice. Fig. 4 Immunofluorescence staining of CD31 in muscle vessels and electron microscopy of capillaryultrastructure. Fig. 5 Quantitative protemics by TMT and biochemistry analysis. Fig. 6 Identification of CD105 and TGF-β1 proteins. Fig. 7 Therapeutic mechanism of hUCMSCs after increased microcirculation permability in diabetic mice.