Dataset from Systemic Allergic Reactions to SARS-CoV-2 Vaccination

Background: Allergic reactions have been reported to occur after vaccination with both the
Pfizer-BioNTech COVID-19 Vaccine and Moderna COVID-19 Vaccine. Allergic reactions range from
mild to severe and include life- threatening anaphylactic reactions, although no deaths have
been reported with either vaccine.

This study is designed with two principal aims:

- To estimate the proportions of systemic allergic reactions to the Pfizer-BioNTech
COVID-19 Vaccine and the Moderna COVID-19 Vaccine in a High-Allergy/Mast Cell Disorder
(HA/MCD) population, and

- If the risk in the HA/MCD is demonstrable, to determine whether the proportions are
higher in the HA/MCD in comparison to a representative population without severe
allergies or mast cell disorders