A LOX-simulated enzyme peptide is used to promote bone healing in diabetes

To investigate the potential osteogenic mechanism of PMLGH, we performed an mRNA expression profiling microarray.Male Sprague Dawley rats (10 weeks old, 320-350 g weight) were used to test the engineered hydrogels in vivo. For gene expression profiling microarray analysis, tibias were harvested at week 3.为探究PMLGH潜在的成骨机制，我们开展了mRNA表达谱微阵列芯片（mRNA expression profiling microarray）分析。选用10周龄、体重320~350g的雄性斯普拉格-道利大鼠（Sprague Dawley rats），实施该工程化水凝胶（engineered hydrogels）的体内测试。在进行本次基因表达谱芯片分析时，于第3周采集胫骨。